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Huei-Fang Liu Selected Research

7- chloro- 6- piperidin- 1- ylquinoline- 5,8- dione

4/20117-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration.
10/20087-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.

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Huei-Fang Liu Research Topics

Disease

9Neoplasms (Cancer)
04/2013 - 12/2004
4Colorectal Neoplasms (Colorectal Cancer)
12/2010 - 01/2006
3Lung Neoplasms (Lung Cancer)
04/2013 - 10/2008
3Carcinoma (Carcinomatosis)
04/2011 - 12/2004
2Breast Neoplasms (Breast Cancer)
04/2013 - 08/2012
2Colonic Neoplasms (Colon Cancer)
04/2013 - 12/2010
2Urinary Bladder Neoplasms (Bladder Cancer)
04/2013 - 11/2007
1Skin Neoplasms (Skin Cancer)
04/2013
1Mitochondrial Diseases (Mitochondrial Disease)
04/2013
1Lymphatic Metastasis
08/2012
1Genomic Instability
10/2010
1Carcinogenesis
07/2007

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
04/2013 - 12/2004
5SurvivinIBA
12/2010 - 12/2004
4SecurinIBA
04/2013 - 01/2006
3p38 Mitogen-Activated Protein KinasesIBA
12/2010 - 07/2007
27- chloro- 6- piperidin- 1- ylquinoline- 5,8- dioneIBA
04/2011 - 10/2008
2Pharmaceutical PreparationsIBA
12/2010 - 10/2008
2baicaleinIBA
10/2010 - 11/2007
2Celecoxib (Celebrex)FDA Link
10/2008 - 07/2007
2Small Interfering RNA (siRNA)IBA
10/2008 - 01/2006
2QuercetinIBA
11/2007 - 12/2004
2FlavonoidsIBA
11/2007 - 12/2004
1ErbB Receptors (EGF Receptor)IBA
04/2013
1Gefitinib (Iressa)FDA Link
04/2013
1Tyrosine Kinase InhibitorsIBA
04/2013
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2013
1Cytochromes c (Cytochrome c)IBA
04/2013
1Caspase 3 (Caspase-3)IBA
04/2013
1Cyclin D1IBA
08/2012
1CateninsIBA
08/2012
1VimentinIBA
08/2012
1Biomarkers (Surrogate Marker)IBA
08/2012
1MicroRNAs (MicroRNA)IBA
08/2012
1benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
12/2010
1Proteasome Endopeptidase Complex (Proteasome)IBA
12/2010
1PlatinumIBA
12/2010
1Proteasome InhibitorsIBA
12/2010
1Oxaliplatin (Eloxatin)FDA LinkGeneric
12/2010
14- (4- fluorophenyl)- 2- (4- hydroxyphenyl)- 5- (4- pyridyl)imidazoleIBA
12/2010
12- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA
10/2008
1CaspasesIBA
10/2008
1Phosphotransferases (Kinase)IBA
11/2007
1GenisteinIBA
11/2007
1Rutin (Rutoside)IBA
11/2007
1Catechin (Z 7300)IBA
11/2007
1baicalinIBA
11/2007
1Cytochalasin BIBA
01/2006

Therapy/Procedure

1Therapeutics
04/2013
1Aftercare (After-Treatment)
12/2010